Design, synthesis and anti-breast cancer properties of butyric ester tethered dihydroartemisinin-isatin hybrids

Fifteen novel butyric ester tethered dihydroartemisinin-isatin hybrids 4a-d and 5a-k were designed, synthesized, and evaluated for cytotoxicity against four human breast cancer cell lines, including MCF-7, MDA-MB-231, MCF-7/ADR and MDA-MB-231/ADR using the MTT method. A significant part of them were...

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Detalles Bibliográficos
Autores principales: Zhao, Shijia, Zhang, Xiaoyan, Tang, Min, Liu, Xiaocheng, Deng, Jialun, Zhou, Wei, Xu, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926453/
https://www.ncbi.nlm.nih.gov/pubmed/36816432
http://dx.doi.org/10.1007/s00044-023-03030-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926453/
https://www.ncbi.nlm.nih.gov/pubmed/36816432
http://dx.doi.org/10.1007/s00044-023-03030-0

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