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Spatio-temporal dynamics enhance cellular diversity, neuronal function and further maturation of human cerebral organoids
The bioengineerined and whole matured human brain organoids stand as highly valuable three-dimensional in vitro brain-mimetic models to recapitulate in vivo brain development, neurodevelopmental and neurodegenerative diseases. Various instructive signals affecting multiple biological processes inclu...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926461/ https://www.ncbi.nlm.nih.gov/pubmed/36788328 http://dx.doi.org/10.1038/s42003-023-04547-1 |