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LINC00478-derived novel cytoplasmic lncRNA LacRNA stabilizes PHB2 and suppresses breast cancer metastasis via repressing MYC targets

BACKGROUND: Metastasis is the predominant cause of mortality in patients with breast cancer. Long noncoding RNAs (lncRNAs) have been shown to drive important phenotypes in tumors, including invasion and metastasis. However, the lncRNAs involved in metastasis and their molecular and cellular mechanis...

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Detalles Bibliográficos
Autores principales: Guo, Rong, Su, Yonghui, Zhang, Qi, Xiu, Bingqiu, Huang, Sheng, Chi, Weiru, Zhang, Liyi, Li, Lun, Hou, Jianjing, Wang, Jia, Chen, Jiajian, Chi, Yayun, Xue, Jingyan, Wu, Jiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926633/
https://www.ncbi.nlm.nih.gov/pubmed/36782197
http://dx.doi.org/10.1186/s12967-023-03967-1