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Low intensity ultrasound-mediated drug-loaded nanoparticles intravaginal drug delivery: an effective synergistic therapy scheme for treatment of vulvovaginal candidiasis

PURPOSE: Vulvovaginal candidiasis (VVC) is a mucosal infection of the female lower genital tract for which treatment using conventional antifungal drugs shows limited effectiveness. Herein, amphotericin B-loaded poly(lactic-co-glycolic acid)-polyethylene glycol (PLGA-PEG) nanoparticles (AmB-NPs) wer...

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Detalles Bibliográficos
Autores principales: Yang, Min, Cao, Yuchao, Zhang, Zhifei, Guo, Jiajun, Hu, Can, Wang, Zhibiao, Du, Yonghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926847/
https://www.ncbi.nlm.nih.gov/pubmed/36782198
http://dx.doi.org/10.1186/s12951-023-01800-x