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Polynucleotide Phosphorylase Mediates a New Mechanism of Persister Formation in Escherichia coli
Despite the identification of many genes and pathways involved in the persistence phenomenon in bacteria, the mechanisms of persistence are not well understood. Here, using Escherichia coli, we identified polynucleotide phosphorylase (PNPase) as a key regulator of persister formation. We constructed...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927094/ https://www.ncbi.nlm.nih.gov/pubmed/36475972 http://dx.doi.org/10.1128/spectrum.01546-22 |