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SARS-CoV-2 Harnesses Host Translational Shutoff and Autophagy To Optimize Virus Yields: the Role of the Envelope (E) Protein

The SARS-CoV-2 virion is composed of four structural proteins: spike (S), nucleocapsid (N), membrane (M), and envelope (E). E spans the membrane a single time and is the smallest, yet most enigmatic of the structural proteins. E is conserved among coronaviruses and has an essential role in virus-med...

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Detalles Bibliográficos
Autores principales: Waisner, Hope, Grieshaber, Brandon, Saud, Rabina, Henke, Wyatt, Stephens, Edward B., Kalamvoki, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927098/
https://www.ncbi.nlm.nih.gov/pubmed/36622177
http://dx.doi.org/10.1128/spectrum.03707-22