Antituberculosis Macozinone Extended-Release Tablets To Enhance Bioavailability: a Pilot Pharmacokinetic Study in Beagle Dogs

Macozinone (MCZ; PBTZ169) is a first-in-class antituberculosis clinical-stage benzothiazinone-based drug candidate. Although its efficacy and safety have been strongly proven in several preclinical and clinical studies, the physicochemical and pharmacokinetic properties specific to MCZ required furt...

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Detalles Bibliográficos
Autores principales: Koryakova, Angela, Shcherbakova, Victoria, Riabova, Olga, Kazaishvili, Yurii, Bolgarin, Roman, Makarov, Vadim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927148/
https://www.ncbi.nlm.nih.gov/pubmed/36507624
http://dx.doi.org/10.1128/spectrum.02327-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927148/
https://www.ncbi.nlm.nih.gov/pubmed/36507624
http://dx.doi.org/10.1128/spectrum.02327-22

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