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Mutation of Phenylalanine 23 of Newcastle Disease Virus Matrix Protein Inhibits Virus Release by Disrupting the Interaction between the FPIV L-Domain and Charged Multivesicular Body Protein 4B

The matrix (M) protein FPIV L-domain is conserved among multiple paramyxoviruses; however, its function and the associated mechanism remain unclear. In this study, the paramyxovirus Newcastle disease virus (NDV) was employed to study the FPIV L-domain. Two recombinant NDV strains, each carrying a si...

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Detalles Bibliográficos
Autores principales: Pei, Yu, Xue, Jia, Teng, Qingyuan, Feng, Delan, Huang, Min, Liang, Rong, Li, Xiao, Zhao, Ye, Zhao, Jing, Zhang, Guozhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927168/
https://www.ncbi.nlm.nih.gov/pubmed/36695580
http://dx.doi.org/10.1128/spectrum.04116-22