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Insect-Specific Chimeric Viruses Potentiated Antiviral Responses and Inhibited Pathogenic Alphavirus Growth in Mosquito Cells

Most alphaviruses are transmitted by mosquito vectors and infect a wide range of vertebrate hosts, with a few exceptions. Eilat virus (EILV) in this genus is characterized by a host range restricted to mosquitoes. Its chimeric viruses have been developed as safe and effective vaccine candidates and...

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Detalles Bibliográficos
Autores principales: Tan, Lu, Zhang, Yiwen, Kim, Dal Young, Li, Runsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927327/
https://www.ncbi.nlm.nih.gov/pubmed/36511715
http://dx.doi.org/10.1128/spectrum.03613-22