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AIDmut-Seq: a Three-Step Method for Detecting Protein-DNA Binding Specificity
Transcriptional factors (TFs) and their regulons make up the gene regulatory networks. Here, we developed a method based on TF-directed activation-induced cytidine deaminase (AID) mutagenesis in combination with genome sequencing, called AIDmut-Seq, to detect TF targets on the genome. AIDmut-Seq inv...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927353/ https://www.ncbi.nlm.nih.gov/pubmed/36533916 http://dx.doi.org/10.1128/spectrum.03783-22 |