Cargando…

AIDmut-Seq: a Three-Step Method for Detecting Protein-DNA Binding Specificity

Transcriptional factors (TFs) and their regulons make up the gene regulatory networks. Here, we developed a method based on TF-directed activation-induced cytidine deaminase (AID) mutagenesis in combination with genome sequencing, called AIDmut-Seq, to detect TF targets on the genome. AIDmut-Seq inv...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Feixuan, Liu, Xiao-Yu, Ni, Lei, Jin, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927353/
https://www.ncbi.nlm.nih.gov/pubmed/36533916
http://dx.doi.org/10.1128/spectrum.03783-22