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AIDmut-Seq: a Three-Step Method for Detecting Protein-DNA Binding Specificity

Transcriptional factors (TFs) and their regulons make up the gene regulatory networks. Here, we developed a method based on TF-directed activation-induced cytidine deaminase (AID) mutagenesis in combination with genome sequencing, called AIDmut-Seq, to detect TF targets on the genome. AIDmut-Seq inv...

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Detalles Bibliográficos
Autores principales:	Li, Feixuan, Liu, Xiao-Yu, Ni, Lei, Jin, Fan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927353/ https://www.ncbi.nlm.nih.gov/pubmed/36533916 http://dx.doi.org/10.1128/spectrum.03783-22

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