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Functional Characterization of 15 Novel Dense Granule Proteins in Toxoplasma gondii Using the CRISPR-Cas9 System

The analysis of the subcellular localization and function of dense granule proteins (GRAs) is of central importance for the understanding of host-parasite interaction and pathogenesis of Toxoplasma gondii infection. Here, we identified 15 novel GRAs and used C-terminal endogenous gene tagging to det...

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Detalles Bibliográficos
Autores principales: Zheng, Xiao-Nan, Wang, Jin-Lei, Elsheikha, Hany M., Wang, Meng, Zhang, Zhi-Wei, Sun, Li-Xiu, Wang, Xin-Cheng, Zhu, Xing-Quan, Li, Ting-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927372/
https://www.ncbi.nlm.nih.gov/pubmed/36515555
http://dx.doi.org/10.1128/spectrum.03078-22