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Deficient Complement Opsonization Impairs Mycobacterium avium Killing by Neutrophils in Cystic Fibrosis

Nontuberculous mycobacteria (NTM), including Mycobacterium avium, are clinically important pathogens in cystic fibrosis (CF). The innate immune response to M. avium remains incompletely understood. We evaluated the role of complement opsonization in neutrophil-mediated killing of M. avium. Killing a...

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Detalles Bibliográficos
Autores principales: Lenhart-Pendergrass, Patricia M., Malcolm, Kenneth C., Wheeler, Emily, Rysavy, Noel M., Poch, Katie, Caceres, Silvia, Calhoun, Kara M., Martiniano, Stacey L., Nick, Jerry A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927418/
https://www.ncbi.nlm.nih.gov/pubmed/36651756
http://dx.doi.org/10.1128/spectrum.03279-22