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Genetic Adaptation and Acquisition of Macrolide Resistance in Haemophilus spp. during Persistent Respiratory Tract Colonization in Chronic Obstructive Pulmonary Disease (COPD) Patients Receiving Long-Term Azithromycin Treatment

Patients with chronic obstructive pulmonary disease (COPD) benefit from the immunomodulatory effect of azithromycin, but long-term administration may alter colonizing bacteria. Our goal was to identify changes in Haemophilus influenzae and Haemophilus parainfluenzae during azithromycin treatment. Fi...

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Detalles Bibliográficos
Autores principales: Carrera-Salinas, Anna, González-Díaz, Aida, Ehrlich, Rachel L., Berbel, Dàmaris, Tubau, Fe, Pomares, Xavier, Garmendia, Junkal, Domínguez, M. Ángeles, Ardanuy, Carmen, Huertas, Daniel, Marín, Alicia, Montón, Conchita, Mell, Joshua Chang, Santos, Salud, Marti, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927455/
https://www.ncbi.nlm.nih.gov/pubmed/36475849
http://dx.doi.org/10.1128/spectrum.03860-22