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Knockout of Targeted Plasmid-Borne β-Lactamase Genes in an Extended-Spectrum-β-Lactamase-Producing Escherichia coli Strain: Impact on Resistance and Proteomic Profile

Resistance to β-lactams is known to be multifactorial, although the underlying mechanisms are not well established. The aim of our study was to develop a system for assessing the phenotypic and proteomic responses of bacteria to antibiotic stress as a result of the loss of selected antimicrobial res...

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Detalles Bibliográficos
Autores principales: Jaén-Luchoro, Daniel, Karlsson, Roger, Busquets, Antonio, Piñeiro-Iglesias, Beatriz, Karami, Nahid, Marathe, Nachiket P., Moore, Edward R. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927464/
https://www.ncbi.nlm.nih.gov/pubmed/36622237
http://dx.doi.org/10.1128/spectrum.03867-22