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Specific Disruption of Ras2 CAAX Proteolysis Alters Its Localization and Function

Many CAAX proteins, such as Ras GTPase, undergo a series of posttranslational modifications at their carboxyl terminus (i.e., cysteine prenylation, endoproteolysis of AAX, and carboxylmethylation). Some CAAX proteins, however, undergo prenylation-only modification, such as Saccharomyces cerevisiae H...

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Detalles Bibliográficos
Autores principales: Ravishankar, Rajani, Hildebrandt, Emily R., Greenway, Grace, Asad, Nadeem, Gore, Sangram, Dore, Timothy M., Schmidt, Walter K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927470/
https://www.ncbi.nlm.nih.gov/pubmed/36602340
http://dx.doi.org/10.1128/spectrum.02692-22