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Insights into the Effects and Mechanism of Andrographolide-Mediated Recovery of Susceptibility of Methicillin-Resistant Staphylococcus aureus to β-Lactam Antibiotics

The frequent resistance associated with β-lactam antibiotics and the high frequency of mutations in β-lactamases constitute a major clinical challenge that can no longer be ignored. Andrographolide (AP), a natural active compound, has been shown to restore susceptibility to β-lactam antibiotics. Flu...

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Detalles Bibliográficos
Autores principales: Ma, Qiang, Wang, Guilai, Li, Na, Wang, Xin, Kang, Xinyun, Mao, Yanni, Wang, Guiqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927479/
https://www.ncbi.nlm.nih.gov/pubmed/36602386
http://dx.doi.org/10.1128/spectrum.02978-22