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Notch signaling, hypoxia, and cancer

Notch signaling is involved in cell fate determination and deregulated in human solid tumors. Hypoxia is an important feature in many solid tumors, which activates hypoxia-induced factors (HIFs) and their downstream targets to promote tumorigenesis and cancer development. Recently, HIFs have been sh...

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Detalles Bibliográficos
Autores principales: Guo, Mingzhou, Niu, Yang, Xie, Min, Liu, Xiansheng, Li, Xiaochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927648/
https://www.ncbi.nlm.nih.gov/pubmed/36798826
http://dx.doi.org/10.3389/fonc.2023.1078768