LepRb(+) cell–specific deletion of Slug mitigates obesity and nonalcoholic fatty liver disease in mice

Leptin exerts its biological actions by activating the long-form leptin receptor (LepRb). LepRb signaling impairment and leptin resistance are believed to cause obesity. The transcription factor Slug — also known as Snai2 — recruits epigenetic modifiers and regulates gene expression by an epigenetic...

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Detalles Bibliográficos
Autores principales: Kim, Min-Hyun, Li, Yuan, Zheng, Qiantao, Jiang, Lin, Myers, Martin G., Wu, Wen-Shu, Rui, Liangyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927931/
https://www.ncbi.nlm.nih.gov/pubmed/36512408
http://dx.doi.org/10.1172/JCI156722

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927931/
https://www.ncbi.nlm.nih.gov/pubmed/36512408
http://dx.doi.org/10.1172/JCI156722

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