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Intestinal epithelial HDAC3 and MHC class II coordinate microbiota-specific immunity

Aberrant immune responses to resident microbes promote inflammatory bowel disease and other chronic inflammatory conditions. However, how microbiota-specific immunity is controlled in mucosal tissues remains poorly understood. Here, we found that mice lacking epithelial expression of microbiota-sens...

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Detalles Bibliográficos
Autores principales: Eshleman, Emily M., Shao, Tzu-Yu, Woo, Vivienne, Rice, Taylor, Engleman, Laura, Didriksen, Bailey J., Whitt, Jordan, Haslam, David B., Way, Sing Sing, Alenghat, Theresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9927950/
https://www.ncbi.nlm.nih.gov/pubmed/36602872
http://dx.doi.org/10.1172/JCI162190