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A cercarial invadolysin interferes with the host immune response and facilitates infection establishment of Schistosoma mansoni

Schistosoma mansoni employs immune evasion and immunosuppression to overcome immune responses mounted by its snail and human hosts. Myriad immunomodulating factors underlie this process, some of which are proteases. Here, we demonstrate that one protease, an invadolysin we have termed SmCI-1, is rel...

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Detalles Bibliográficos
Autores principales: Hambrook, Jacob R., Hanington, Patrick C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928134/
https://www.ncbi.nlm.nih.gov/pubmed/36730464
http://dx.doi.org/10.1371/journal.ppat.1010884