LRRC3B and its promoter hypomethylation status predicts response to anti-PD-1 based immunotherapy

BACKGROUND: The leucine rich repeat containing 3B (LRRC3B) gene is a tumor suppressor gene involved in the anti-tumor immune microenvironment. Expression of LRRC3B and DNA methylation at the LRRC3B promoter region may serve as a useful marker to predict response to anti-PD-1 therapy. However, no stu...

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Detalles Bibliográficos
Autores principales: Luo, Linfeng, Fu, Sha, Du, Wei, He, Li-na, Zhang, Xuanye, Wang, Yixing, Zhou, Yixin, Hong, Shaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928207/
https://www.ncbi.nlm.nih.gov/pubmed/36798137
http://dx.doi.org/10.3389/fimmu.2023.959868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928207/
https://www.ncbi.nlm.nih.gov/pubmed/36798137
http://dx.doi.org/10.3389/fimmu.2023.959868

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