Nimesulide, a COX-2 inhibitor, sensitizes pancreatic cancer cells to TRAIL-induced apoptosis by promoting DR5 clustering †

Nimesulide is a nonsteroidal anti-inflammatory drug and a COX-2 inhibitor with antitumor and antiproliferative activities that induces apoptosis in oral, esophagus, breast, and pancreatic cancer cells. Despite being removed from the market due to hepatotoxicity, nimesulide is still an important rese...

Descripción completa

Detalles Bibliográficos
Autores principales: Vunnam, Nagamani, Young, Malaney C., Liao, Elly E., Lo, Chih Hung, Huber, Evan, Been, MaryJane, Thomas, David D., Sachs, Jonathan N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928464/
https://www.ncbi.nlm.nih.gov/pubmed/36775838
http://dx.doi.org/10.1080/15384047.2023.2176692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928464/
https://www.ncbi.nlm.nih.gov/pubmed/36775838
http://dx.doi.org/10.1080/15384047.2023.2176692

Ejemplares similares