The major role of sarA in limiting Staphylococcus aureus extracellular protease production in vitro is correlated with decreased virulence in diverse clinical isolates in osteomyelitis

We previously demonstrated that MgrA, SarA, SarR, SarS, SarZ, and Rot bind at least three of the four promoters associated with genes encoding primary extracellular proteases in Staphylococcus aureus (Aur, ScpA, SspA/SspB, SplA-F). We also showed that mutation of sarA results in a greater increase i...

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Detalles Bibliográficos
Autores principales: Campbell, Mara J., Beenken, Karen E., Ramirez, Aura M., Smeltzer, Mark S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928472/
https://www.ncbi.nlm.nih.gov/pubmed/36748843
http://dx.doi.org/10.1080/21505594.2023.2175496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928472/
https://www.ncbi.nlm.nih.gov/pubmed/36748843
http://dx.doi.org/10.1080/21505594.2023.2175496

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