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Neuroprotective effects of a lead compound from coral via modulation of the orphan nuclear receptor Nurr1

AIMS: To screen coral‐derived compounds with neuroprotective activity and clarify the potential mechanism of lead compounds. METHODS: The lead compounds with neuroprotective effects were screened by H(2)O(2) and 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPP(+))‐induced cell damage models in SH‐S...

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Detalles Bibliográficos
Autores principales: Su, Jian‐Wei, Yang, Pei, Xing, Mei‐Mei, Chen, Bao, Xie, Xia‐Hong, Ding, Jian‐Hua, Lu, Ming, Liu, Yang, Guo, Yue‐Wei, Hu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928544/
https://www.ncbi.nlm.nih.gov/pubmed/36419251
http://dx.doi.org/10.1111/cns.14025