Cargando…

Neuroprotective effects of a lead compound from coral via modulation of the orphan nuclear receptor Nurr1

AIMS: To screen coral‐derived compounds with neuroprotective activity and clarify the potential mechanism of lead compounds. METHODS: The lead compounds with neuroprotective effects were screened by H(2)O(2) and 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPP(+))‐induced cell damage models in SH‐S...

Descripción completa

Detalles Bibliográficos
Autores principales:	Su, Jian‐Wei, Yang, Pei, Xing, Mei‐Mei, Chen, Bao, Xie, Xia‐Hong, Ding, Jian‐Hua, Lu, Ming, Liu, Yang, Guo, Yue‐Wei, Hu, Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928544/ https://www.ncbi.nlm.nih.gov/pubmed/36419251 http://dx.doi.org/10.1111/cns.14025

Ejemplares similares

Dichotomous roles for the orphan nuclear receptor NURR1 in breast cancer
por: Llopis, Shawn, et al.
Publicado: (2013)

The Orphan Nuclear Receptor Nurr1 Restricts the Proliferation of Hematopoietic Stem Cells
por: Sirin, Olga, et al.
Publicado: (2010)

Potent synthetic and endogenous ligands for the adopted orphan nuclear receptor Nurr1
por: Jang, Yongwoo, et al.
Publicado: (2021)

Multiple signaling pathways regulate the transcriptional activity of the orphan nuclear receptor NURR1
por: Sacchetti, Paola, et al.
Publicado: (2006)

The orphan nuclear receptor Nurr1 is responsive to non-steroidal anti-inflammatory drugs
por: Willems, Sabine, et al.
Publicado: (2020)

Orphan nuclear receptor Nurr1 promotes Helicobacter pylori-associated gastric carcinogenesis by directly enhancing CDK4 expression
por: Shang, Wenjing, et al.
Publicado: (2020)

Nurr1 Modulation Mediates Neuroprotective Effects of Statins
por: Willems, Sabine, et al.
Publicado: (2022)

Nemo-like kinase as a negative regulator of nuclear receptor Nurr1 gene transcription in prostate cancer
por: Wang, Jian, et al.
Publicado: (2016)

Expression of Nuclear Orphan Receptors Ngfi-B/Tr3, Nurr1 And Nor-1 after Global Brain Ischemia in Rat
por: Schmidt-Kastner, Rainald, et al.
Publicado: (2001)

Integrative analysis reveals structural basis for transcription activation of Nurr1 and Nurr1-RXRα heterodimer
por: Zhao, Mohan, et al.
Publicado: (2022)

Chemoprevention of Skin Cancer with 1,1-Bis (3′-Indolyl)-1-(Aromatic) Methane Analog through Induction of the Orphan Nuclear Receptor, NR4A2 (Nurr1)
por: Boakye, Cedar H. A., et al.
Publicado: (2013)

Quantitative Immunohistochemistry to Measure Regional Expression of Nurr1 in the Brain and the Effect of the Nurr1 Heterozygous Genotype
por: Kummari, Evangel, et al.
Publicado: (2021)

NURR1 Impairment in Multiple Sclerosis
por: Montarolo, Francesca, et al.
Publicado: (2019)

The role of NURR1 in metabolic abnormalities of Parkinson’s disease
por: Al-Nusaif, Murad, et al.
Publicado: (2022)

Inhibition of Nur77/Nurr1 leads to inefficient clonal deletion of self- reactive T cells
Publicado: (1996)

Bioactive Compounds from a Gorgonian Coral Echinomuricea sp. (Plexauridae)
por: Chung, Hsu-Ming, et al.
Publicado: (2012)

Transplantation of Nurr1‐overexpressing neural stem cells and microglia for treating parkinsonian rats
por: Qian, Yuan, et al.
Publicado: (2019)

Nurr1 expression is modified by inflammation in microglia
por: Lallier, Scott W., et al.
Publicado: (2016)

Testicular orphan nuclear receptor 4-associated protein 16 promotes non-small cell lung carcinoma by activating estrogen receptor β and blocking testicular orphan nuclear receptor 2
por: FANG, FANG, et al.
Publicado: (2012)

PIASγ Enhanced SUMO-2 Modification of Nurr1 Activation-Function-1 Domain Limits Nurr1 Transcriptional Synergy
por: Arredondo, Cristian, et al.
Publicado: (2013)

Lipid-sensors, enigmatic-orphan and orphan nuclear receptors as therapeutic targets in breast-cancer
por: Garattini, Enrico, et al.
Publicado: (2016)

Nurr1 regulates Top IIβ and functions in axon genesis of mesencephalic dopaminergic neurons
por: Heng, Xin, et al.
Publicado: (2012)

Molecular characterization and analysis of the porcine NURR1 gene
por: Larsen, Knud, et al.
Publicado: (2016)

NURR1 Downregulation Favors Osteoblastic Differentiation of MSCs
por: Di Benedetto, Adriana, et al.
Publicado: (2017)

Ligand Dependent Switch from RXR Homo- to RXR-NURR1 Heterodimerization
por: Scheepstra, Marcel, et al.
Publicado: (2017)

An autoregulatory loop controlling orphan nuclear receptor DAX-1 gene expression by orphan nuclear receptor ERRγ
por: Park, Yun-Yong, et al.
Publicado: (2005)

An autoregulatory loop controlling orphan nuclear receptor DAX-1 gene expression by orphan nuclear receptor ERRγ
por: Park, Yun-Yong, et al.
Publicado: (2018)

An autoregulatory loop controlling orphan nuclear receptor DAX-1 gene expression by orphan nuclear receptor ERRγ
por: Park, Yun-Yong, et al.
Publicado: (2019)

Correction for Zhao et al., Integrative analysis reveals structural basis for transcription activation of Nurr1 and Nurr1-RXRα heterodimer
Publicado: (2023)

Selective brain penetrable Nurr1 transactivator for treating Parkinson's disease
por: Wang, Jun, et al.
Publicado: (2016)

Orphan Drugs, Compounded Medication and Pharmaceutical Commons
por: Hendrickx, Kim, et al.
Publicado: (2021)

Metabolic Insight Into the Neuroprotective Effect of Tao-He-Cheng-Qi (THCQ) Decoction on ICH Rats Using Untargeted Metabolomics
por: Yang, Rui-Pei, et al.
Publicado: (2021)

The lifelong maintenance of mesencephalic dopaminergic neurons by Nurr1 and engrailed
por: Alavian, Kambiz N, et al.
Publicado: (2014)

NURR1 deficiency is associated to ADHD-like phenotypes in mice
por: Montarolo, Francesca, et al.
Publicado: (2019)

Nurr1 Is Not an Essential Regulator of BDNF in Mouse Cortical Neurons
por: Abdollahi, Mona, et al.
Publicado: (2022)

Advances in NURR1-Regulated Neuroinflammation Associated with Parkinson’s Disease
por: Al-Nusaif, Murad, et al.
Publicado: (2022)

The Nurr1 Ligand,1,1-bis(3′-Indolyl)-1-(p-Chlorophenyl)Methane, Modulates Glial Reactivity and Is Neuroprotective in MPTP-Induced Parkinsonism
por: Hammond, Sean L., et al.
Publicado: (2018)

The role of the orphan nuclear receptor COUP-TFII in tumorigenesis
por: Xu, Mafei, et al.
Publicado: (2015)

Orphan nuclear receptor TLX promotes immunosuppression via its transcriptional activation of PD-L1 in glioma
por: Zhou, Jiayi, et al.
Publicado: (2021)

Orphan Nuclear Receptor Nur77 Regulates Androgen Receptor Gene Expression in Mouse Ovary
por: Dai, Anyi, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_7iu66rpm6i5v5uunkucbjlqamn