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Alpha‐Asarone modulates kynurenine disposal in muscle and mediates resilience to stress‐induced depression via PGC‐1α induction

INTRODUCTION: Kynurenine (KYN) accumulation in periphery induces brain injury, responsible for depression. α‐Asarone is a simple phenylpropanoids that exerts beneficial effects on central nervous system. However, the effect of α‐asarone on periphery is unexplored. AIMS: Here, we investigated its pro...

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Detalles Bibliográficos
Autores principales: Yan, Lu, Liu, Chu‐han, Xu, Li, Qian, Yi‐yun, Song, Ping‐ping, Wei, Min, Liu, Bao‐lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928554/
https://www.ncbi.nlm.nih.gov/pubmed/36575869
http://dx.doi.org/10.1111/cns.14030