In vivo inhibition of epileptiform afterdischarges in rat hippocampus by light‐activated chloride channel, stGtACR2

AIMS: The blue light‐sensitive chloride‐conducting opsin, stGtACR2, provides potent optogenetic silencing of neurons. The present study investigated whether activation of stGtACR2 in granule cells of the dentate gyrus (DG) inhibits epileptic afterdischarges in a rat model. METHODS: Rats were bilater...

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Detalles Bibliográficos
Autores principales: Acharya, Anirudh R., Larsen, Lars Emil, Delbeke, Jean, Wadman, Wytse J., Vonck, Kristl, Meurs, Alfred, Boon, Paul, Raedt, Robrecht
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928558/
https://www.ncbi.nlm.nih.gov/pubmed/36482869
http://dx.doi.org/10.1111/cns.14029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928558/
https://www.ncbi.nlm.nih.gov/pubmed/36482869
http://dx.doi.org/10.1111/cns.14029

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