Cargando…
In vivo inhibition of epileptiform afterdischarges in rat hippocampus by light‐activated chloride channel, stGtACR2
AIMS: The blue light‐sensitive chloride‐conducting opsin, stGtACR2, provides potent optogenetic silencing of neurons. The present study investigated whether activation of stGtACR2 in granule cells of the dentate gyrus (DG) inhibits epileptic afterdischarges in a rat model. METHODS: Rats were bilater...
Autores principales: | Acharya, Anirudh R., Larsen, Lars Emil, Delbeke, Jean, Wadman, Wytse J., Vonck, Kristl, Meurs, Alfred, Boon, Paul, Raedt, Robrecht |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928558/ https://www.ncbi.nlm.nih.gov/pubmed/36482869 http://dx.doi.org/10.1111/cns.14029 |
Ejemplares similares
-
Attenuation of Hippocampal Evoked Potentials in vivo by Activation of GtACR2, an Optogenetic Chloride Channel
por: Acharya, Anirudh R., et al.
Publicado: (2021) -
Level of hM4D(Gi) DREADD Expression Determines Inhibitory and Neurotoxic Effects in the Hippocampus
por: Goossens, Marie-Gabrielle, et al.
Publicado: (2021) -
Continuous theta burst stimulation for drug-resistant epilepsy
por: Carrette, Sofie, et al.
Publicado: (2022) -
A Feasibility Study to Investigate Chemogenetic Modulation of the Locus Coeruleus by Means of Single Unit Activity
por: Stevens, Latoya, et al.
Publicado: (2020) -
Ex Vivo Feedback Control of Neurotransmission Using a Photocaged Adenosine A1 Receptor Agonist
por: Craey, Erine, et al.
Publicado: (2022)