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Multi-modular structure of the gene regulatory network for specification and commitment of murine T cells
T cells develop from multipotent progenitors by a gradual process dependent on intrathymic Notch signaling and coupled with extensive proliferation. The stages leading them to T-cell lineage commitment are well characterized by single-cell and bulk RNA analyses of sorted populations and by direct me...
Autores principales: | Shin, Boyoung, Rothenberg, Ellen V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928580/ https://www.ncbi.nlm.nih.gov/pubmed/36817475 http://dx.doi.org/10.3389/fimmu.2023.1108368 |
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