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CanRisk-Prostate: A Comprehensive, Externally Validated Risk Model for the Prediction of Future Prostate Cancer

Prostate cancer (PCa) is highly heritable. No validated PCa risk model currently exists. We therefore sought to develop a genetic risk model that can provide personalized predicted PCa risks on the basis of known moderate- to high-risk pathogenic variants, low-risk common genetic variants, and expli...

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Detalles Bibliográficos
Autores principales: Nyberg, Tommy, Brook, Mark N., Ficorella, Lorenzo, Lee, Andrew, Dennis, Joe, Yang, Xin, Wilcox, Naomi, Dadaev, Tokhir, Govindasami, Koveela, Lush, Michael, Leslie, Goska, Lophatananon, Artitaya, Muir, Kenneth, Bancroft, Elizabeth, Easton, Douglas F., Tischkowitz, Marc, Kote-Jarai, Zsofia, Eeles, Rosalind, Antoniou, Antonis C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928632/
https://www.ncbi.nlm.nih.gov/pubmed/36493335
http://dx.doi.org/10.1200/JCO.22.01453