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CanRisk-Prostate: A Comprehensive, Externally Validated Risk Model for the Prediction of Future Prostate Cancer
Prostate cancer (PCa) is highly heritable. No validated PCa risk model currently exists. We therefore sought to develop a genetic risk model that can provide personalized predicted PCa risks on the basis of known moderate- to high-risk pathogenic variants, low-risk common genetic variants, and expli...
Autores principales: | Nyberg, Tommy, Brook, Mark N., Ficorella, Lorenzo, Lee, Andrew, Dennis, Joe, Yang, Xin, Wilcox, Naomi, Dadaev, Tokhir, Govindasami, Koveela, Lush, Michael, Leslie, Goska, Lophatananon, Artitaya, Muir, Kenneth, Bancroft, Elizabeth, Easton, Douglas F., Tischkowitz, Marc, Kote-Jarai, Zsofia, Eeles, Rosalind, Antoniou, Antonis C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928632/ https://www.ncbi.nlm.nih.gov/pubmed/36493335 http://dx.doi.org/10.1200/JCO.22.01453 |
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