Impact of age‐dependent red blood cell parameters on α‐globin gene genotyping in children

When screening for α‐thalassemia in children, adult cut‐offs for mean corpuscular volume (MCV) and mean corpuscular hemoglobin (MCH) are generally applied to guide genetic evaluation. However, the normal ranges for MCV and MCH are lower in children than in adults, so we hypothesized that using age‐m...

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Detalles Bibliográficos
Autores principales: Nissen, Peter H., Narvestad‐Bøttger, Helene, Kristensen, Helle Pilgaard, Winther‐Larsen, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Sickle Cell, Thrombosis, and Classical Haematology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928656/
https://www.ncbi.nlm.nih.gov/pubmed/36819175
http://dx.doi.org/10.1002/jha2.627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928656/
https://www.ncbi.nlm.nih.gov/pubmed/36819175
http://dx.doi.org/10.1002/jha2.627

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