Conformational ensemble of the NSP1 CTD in SARS-CoV-2: Perspectives from the free energy landscape

The nonstructural protein-1 (NSP1) of the severe acute respiratory syndrome-associated coronavirus 2 plays a crucial role in the translational shutdown and immune evasion inside host cells. Despite its known intrinsic disorder, the C-terminal domain (CTD) of NSP1 has been reported to form a double [...

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Detalles Bibliográficos
Autores principales: Dutta, Pallab, Kshirsagar, Abhay, Bibekar, Parth, Sengupta, Neelanjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928668/
https://www.ncbi.nlm.nih.gov/pubmed/36793215
http://dx.doi.org/10.1016/j.bpj.2023.02.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928668/
https://www.ncbi.nlm.nih.gov/pubmed/36793215
http://dx.doi.org/10.1016/j.bpj.2023.02.010

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