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Conformational ensemble of the NSP1 CTD in SARS-CoV-2: Perspectives from the free energy landscape
The nonstructural protein-1 (NSP1) of the severe acute respiratory syndrome-associated coronavirus 2 plays a crucial role in the translational shutdown and immune evasion inside host cells. Despite its known intrinsic disorder, the C-terminal domain (CTD) of NSP1 has been reported to form a double [...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Biophysical Society
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928668/ https://www.ncbi.nlm.nih.gov/pubmed/36793215 http://dx.doi.org/10.1016/j.bpj.2023.02.010 |