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HRAS Mutations Define a Distinct Subgroup in Head and Neck Squamous Cell Carcinoma

In head and neck squamous cell carcinoma (HNSCC), HRAS mutation is a new actionable oncogene driver. We aimed to evaluate HRAS mutational variants, comutation profile, and survival outcomes of this molecularly defined population. METHODS: We leveraged four deidentified patient data sets with HRAS-mu...

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Detalles Bibliográficos
Autores principales: Coleman, Niamh, Marcelo, Kathrina L., Hopkins, Julia F., Khan, Nusrat Israr, Du, Robyn, Hong, Lingzhi, Park, Edward, Balsara, Binaifer, Leoni, Mollie, Pickering, Curtis, Myers, Jeffrey, Heymach, John, Albacker, Lee A., Hong, David, Gillison, Maura, Le, Xiuning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928766/
https://www.ncbi.nlm.nih.gov/pubmed/36603172
http://dx.doi.org/10.1200/PO.22.00211