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Impact of gene alterations on clinical outcome in young adults with myelodysplastic syndromes

Young adults with myelodysplastic syndrome (MDS) are rare, and the clinical significance of driver mutations has not yet been analysed. We analysed the gene mutations and copy number alterations (CNAs) in younger MDS patients using next-generation sequencing, targeting 68 genes that were recurrently...

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Detalles Bibliográficos
Autores principales: Konishi, Tatsuya, Sadato, Daichi, Toya, Takashi, Hirama, Chizuko, Kishida, Yuya, Nagata, Akihito, Yamada, Yuta, Shingai, Naoki, Shimizu, Hiroaki, Najima, Yuho, Kobayashi, Takeshi, Haraguchi, Kyoko, Okuyama, Yoshiki, Harada, Hironori, Ohashi, Kazuteru, Harada, Yuka, Doki, Noriko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929038/
https://www.ncbi.nlm.nih.gov/pubmed/36788335
http://dx.doi.org/10.1038/s41598-023-29794-4