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BRD7 inhibits enhancer activity and expression of BIRC2 to suppress tumor growth and metastasis in nasopharyngeal carcinoma

BRD7 functions as a crucial tumor suppressor in numerous malignancies including nasopharyngeal carcinoma (NPC). However, its function and exact mechanisms involved in tumor progression are not well understood. Here, we found that the B7BS was a potential enhancer region of BIRC2, and BRD7 negatively...

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Detalles Bibliográficos
Autores principales: Li, Mengna, Wei, Yanmei, Liu, Yukun, Wei, Jianxia, Zhou, Xiangting, Duan, Yumei, Chen, Shipeng, Xue, Changning, Zhan, Yuting, Zheng, Lemei, Deng, Hongyu, Tang, Faqing, Fan, Songqing, Xiong, Wei, Li, Guiyuan, Tan, Ming, Zhou, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929072/
https://www.ncbi.nlm.nih.gov/pubmed/36788209
http://dx.doi.org/10.1038/s41419-023-05632-3