Towards Translation of PqsR Inverse Agonists: From In Vitro Efficacy Optimization to In Vivo Proof‐of‐Principle

Pseudomonas aeruginosa (PA) is an opportunistic human pathogen, which is involved in a wide range of dangerous infections. It develops alarming resistances toward antibiotic treatment. Therefore, alternative strategies, which suppress pathogenicity or synergize with antibiotic treatments are in grea...

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Detalles Bibliográficos
Autores principales: Hamed, Mostafa M., Abdelsamie, Ahmed S., Rox, Katharina, Schütz, Christian, Kany, Andreas M., Röhrig, Teresa, Schmelz, Stefan, Blankenfeldt, Wulf, Arce‐Rodriguez, Alejandro, Borrero‐de Acuña, José Manuel, Jahn, Dieter, Rademacher, Jessica, Ringshausen, Felix C., Cramer, Nina, Tümmler, Burkhard, Hirsch, Anna K. H., Hartmann, Rolf W., Empting, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929129/
https://www.ncbi.nlm.nih.gov/pubmed/36596691
http://dx.doi.org/10.1002/advs.202204443

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929129/
https://www.ncbi.nlm.nih.gov/pubmed/36596691
http://dx.doi.org/10.1002/advs.202204443

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