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Short-term exposure to dimethyl fumarate (DMF) inhibits LPS-induced IκBζ expression in macrophages

Background: The pharmacological activity of dimethyl fumarate (DMF) in treating psoriasis and multiple sclerosis (MS) is not fully understood. DMF is hydrolysed to monomethyl fumarate (MMF) in vivo, which is believed to account for the therapeutic effects of DMF. However, previous studies have provi...

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Detalles Bibliográficos
Autores principales: Zhang, Yong, Tang, Jingshu, Zhou, Yujun, Xiao, Qiong, Chen, Qiuyu, Wang, Hongyue, Lan, Jiaqi, Wu, Lei, Peng, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929133/
https://www.ncbi.nlm.nih.gov/pubmed/36817140
http://dx.doi.org/10.3389/fphar.2023.1114897