Targeting the Lysosomal Degradation of Rab22a‐NeoF1 Fusion Protein for Osteosarcoma Lung Metastasis

Rab22a‐NeoF fusion protein has recently been reported as a promising target for osteosarcoma lung metastasis. However, how this fusion protein is regulated in cells remains unknown. Here, using multiple screenings, it is reported that Rab22a‐NeoF1 fusion protein is degraded by an E3 ligase STUB1 via...

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Detalles Bibliográficos
Autores principales: Zeng, Cuiling, Zhong, Li, Liu, Wenqiang, Zhang, Yu, Yu, Xinhao, Wang, Xin, Zhang, Ruhua, Kang, Tiebang, Liao, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929137/
https://www.ncbi.nlm.nih.gov/pubmed/36529692
http://dx.doi.org/10.1002/advs.202205483

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929137/
https://www.ncbi.nlm.nih.gov/pubmed/36529692
http://dx.doi.org/10.1002/advs.202205483

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