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Modifications of the endosomal compartment in fibroblasts from sporadic Alzheimer’s disease patients are associated with cognitive impairment

Morphological alterations of the endosomal compartment have been widely described in post-mortem brains from Alzheimer’s disease (AD) patients and subjects with Down syndrome (DS) who are at high risk for AD. Immunostaining with antibodies against endosomal markers such as Early Endosome Antigen 1 (...

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Detalles Bibliográficos
Autores principales: Xicota, Laura, Lagarde, Julien, Eysert, Fanny, Grenier-Boley, Benjamin, Rivals, Isabelle, Botté, Alexandra, Forlani, Sylvie, Landron, Sophie, Gautier, Clément, Gabriel, Cecilia, Bottlaender, Michel, Lambert, Jean-Charles, Chami, Mounia, Sarazin, Marie, Potier, Marie-Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929231/
https://www.ncbi.nlm.nih.gov/pubmed/36788216
http://dx.doi.org/10.1038/s41398-023-02355-z