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Modifications of the endosomal compartment in fibroblasts from sporadic Alzheimer’s disease patients are associated with cognitive impairment
Morphological alterations of the endosomal compartment have been widely described in post-mortem brains from Alzheimer’s disease (AD) patients and subjects with Down syndrome (DS) who are at high risk for AD. Immunostaining with antibodies against endosomal markers such as Early Endosome Antigen 1 (...
Autores principales: | Xicota, Laura, Lagarde, Julien, Eysert, Fanny, Grenier-Boley, Benjamin, Rivals, Isabelle, Botté, Alexandra, Forlani, Sylvie, Landron, Sophie, Gautier, Clément, Gabriel, Cecilia, Bottlaender, Michel, Lambert, Jean-Charles, Chami, Mounia, Sarazin, Marie, Potier, Marie-Claude |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929231/ https://www.ncbi.nlm.nih.gov/pubmed/36788216 http://dx.doi.org/10.1038/s41398-023-02355-z |
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