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RIIβ‐PKA in GABAergic Neurons of Dorsal Median Hypothalamus Governs White Adipose Browning

The RIIβ subunit of  cAMP‐dependent protein kinase A (PKA) is expressed in the brain and adipose tissue. RIIβ‐knockout mice show leanness and increased UCP1 in brown adipose tissue. The authors have previously reported that RIIβ reexpression in hypothalamic GABAergic neurons rescues the leanness. Ho...

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Detalles Bibliográficos
Autores principales: Wang, Bingwei, Zhao, Miao, Su, Zhijie, Jin, Baohua, Yang, Xiaoning, Zhang, Chenyu, Guo, Bingbing, Li, Jiebo, Hong, Weili, Liu, Jiarui, Zhao, Yun, Hou, Yujia, Lai, Futing, Zhang, Wei, Qin, Lihua, Zhang, Weiguang, Luo, Jianyuan, Zheng, Ruimao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929258/
https://www.ncbi.nlm.nih.gov/pubmed/36529950
http://dx.doi.org/10.1002/advs.202205173