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Defined Microenvironments Trigger In Vitro Gastrulation in Human Pluripotent Stem Cells

Gastrulation is a stage in embryo development where three germ layers arise to dictate the human body plan. In vitro models of gastrulation have been demonstrated by treating pluripotent stem cells with soluble morphogens to trigger differentiation. However, in vivo gastrulation is a multistage proc...

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Detalles Bibliográficos
Autores principales: Srivastava, Pallavi, Romanazzo, Sara, Kopecky, Chantal, Nemec, Stephanie, Ireland, Jake, Molley, Thomas G., Lin, Kang, Jayathilaka, Pavithra B., Pandzic, Elvis, Yeola, Avani, Chandrakanthan, Vashe, Pimanda, John, Kilian, Kristopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929265/
https://www.ncbi.nlm.nih.gov/pubmed/36519269
http://dx.doi.org/10.1002/advs.202203614