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Developmental exposure to domoic acid targets reticulospinal neurons and leads to aberrant myelination in the spinal cord

Harmful algal blooms (HABs) produce neurotoxins that affect human health. Developmental exposure of zebrafish embryos to the HAB toxin domoic acid (DomA) causes myelin defects, loss of reticulospinal neurons, and behavioral deficits. However, it is unclear whether DomA primarily targets myelin sheat...

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Detalles Bibliográficos
Autores principales: Panlilio, Jennifer M., Hammar, Katherine M., Aluru, Neelakanteswar, Hahn, Mark E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929266/
https://www.ncbi.nlm.nih.gov/pubmed/36788234
http://dx.doi.org/10.1038/s41598-023-28166-2