A combined analysis of bulk and single-cell sequencing data reveals metabolic enzyme, pyruvate dehydrogenase E1 subunit beta (PDHB), as a prediction biomarker for the tumor immune response and immunotherapy

Pyruvate dehydrogenase E1 subunit beta (PDHB) is located in mitochondria and catalyzes the conversion of glucose-derived acetyl-CoA. The detailed roles of PDHB in human cancers is unclear. Here, through comprehensive bioinformatics analysis, we found that PDHB was aberrantly expressed in multiple hu...

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Detalles Bibliográficos
Autores principales: Zhang, Fan, Yan, Yuanliang, Liang, Qiuju, Liu, Yuanhong, Wu, Geting, Xu, Zhijie, Yang, Keda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929299/
https://www.ncbi.nlm.nih.gov/pubmed/36816316
http://dx.doi.org/10.1016/j.heliyon.2023.e13456

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929299/
https://www.ncbi.nlm.nih.gov/pubmed/36816316
http://dx.doi.org/10.1016/j.heliyon.2023.e13456

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