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Sequence dependent UV damage of complete pools of oligonucleotides

Understanding the sequence-dependent DNA damage formation requires probing a complete pool of sequences over a wide dose range of the damage-causing exposure. We used high throughput sequencing to simultaneously obtain the dose dependence and quantum yields for oligonucleotide damages for all possib...

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Detalles Bibliográficos
Autores principales: Kufner, Corinna L., Krebs, Stefan, Fischaleck, Marlis, Philippou-Massier, Julia, Blum, Helmut, Bucher, Dominik B., Braun, Dieter, Zinth, Wolfgang, Mast, Christof B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929323/
https://www.ncbi.nlm.nih.gov/pubmed/36788271
http://dx.doi.org/10.1038/s41598-023-29833-0