A genome-wide CRISPR-Cas9 knockout screen identifies FSP1 as the warfarin-resistant vitamin K reductase

Vitamin K is a vital micronutrient implicated in a variety of human diseases. Warfarin, a vitamin K antagonist, is the most commonly prescribed oral anticoagulant. Patients overdosed on warfarin can be rescued by administering high doses of vitamin K because of the existence of a warfarin-resistant...

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Detalles Bibliográficos
Autores principales: Jin, Da-Yun, Chen, Xuejie, Liu, Yizhou, Williams, Craig M., Pedersen, Lars C., Stafford, Darrel W., Tie, Jian-Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929328/
https://www.ncbi.nlm.nih.gov/pubmed/36788244
http://dx.doi.org/10.1038/s41467-023-36446-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929328/
https://www.ncbi.nlm.nih.gov/pubmed/36788244
http://dx.doi.org/10.1038/s41467-023-36446-8

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