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ADR3, a next generation i-body to human RANKL, inhibits osteoclast formation and bone resorption
Osteoporosis is a chronic skeletal condition characterized by low bone mass and deteriorated microarchitecture of bone tissue and puts tens of millions of people at high risk of fractures. New therapeutic agents like i-bodies, a class of next-generation single-domain antibodies, are needed to overco...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929471/ https://www.ncbi.nlm.nih.gov/pubmed/36634847 http://dx.doi.org/10.1016/j.jbc.2023.102889 |